Alright. Well, Murphy would be a pirate queen, with her own ship. Kirmani would be her snarky first mate. Harry would be some sort of Jamaican hoodoo guy who Murphy needs to help her solve various supernatural things. Only, instead of it being for the greater good, it would be for treasure. Bob would remain probably as he is - a cursed guy in a skull that belongs to Harry. And Anna could be Murphy's adorable piratey daughter.